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The Tem contain large amounts of perforins, which is a cytotoxic agent usedby CD8 CTL to destroy targeted cells.
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Numerous secretoryvesicles (G) in the base of the cell aresecreted in the direction ofthe arrowsacross the basal lamina and into the connective tissue (C7).En,endothelium ofcapillary; M, mitochondria; rER, roughendoplasmic reticulum;sER,smooth endoplasmic reticulum.
Onset and durationdepends on the site, the drug, its concentrationand form, e.g.
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